KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERO1L
All Species:
30.3
Human Site:
S223
Identified Species:
41.67
UniProt:
Q96HE7
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96HE7
NP_055399.1
468
54393
S223
R
P
L
N
P
L
A
S
G
Q
G
T
S
E
E
Chimpanzee
Pan troglodytes
XP_509950
468
54427
S223
R
P
L
N
P
L
A
S
G
Q
G
K
S
E
E
Rhesus Macaque
Macaca mulatta
XP_001103965
468
54383
S223
R
P
L
N
P
L
A
S
G
Q
G
K
S
E
E
Dog
Lupus familis
XP_547813
468
54343
S223
R
P
L
N
P
L
A
S
G
Q
G
K
S
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8R180
464
54066
S219
T
I
Q
R
P
L
A
S
G
R
G
K
S
K
E
Rat
Rattus norvegicus
Q8R4A1
464
54000
S219
T
I
Q
R
P
L
A
S
G
Q
G
K
H
K
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515503
465
53870
S220
R
P
L
S
P
L
A
S
G
Q
G
K
S
E
E
Chicken
Gallus gallus
XP_421473
463
52908
S218
N
V
K
R
P
L
T
S
G
R
G
D
D
G
G
Frog
Xenopus laevis
Q6DD71
465
53720
S221
R
P
L
N
P
L
T
S
S
R
G
E
N
E
G
Zebra Danio
Brachydanio rerio
Q7T3D1
489
56571
A214
N
R
P
L
N
P
L
A
S
N
S
G
D
D
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3A6
483
55641
E233
N
C
F
G
G
N
N
E
T
A
N
K
F
S
N
Honey Bee
Apis mellifera
XP_623933
471
55049
R225
I
Y
M
E
N
C
F
R
P
E
N
S
P
H
N
Nematode Worm
Caenorhab. elegans
Q7YTU4
478
55136
K218
K
P
D
P
K
F
D
K
N
F
L
T
N
P
S
Sea Urchin
Strong. purpuratus
XP_796844
897
101920
T649
R
P
E
T
P
E
S
T
A
T
T
Y
E
S
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C7S7
469
53812
G243
V
L
Y
K
L
I
S
G
L
H
S
S
I
S
M
Baker's Yeast
Sacchar. cerevisiae
Q03103
563
65014
F223
E
S
L
A
K
D
A
F
Y
R
L
V
S
G
F
Red Bread Mold
Neurospora crassa
Q7SEY9
668
75589
T222
K
S
A
S
L
G
D
T
Y
S
V
P
K
N
P
Conservation
Percent
Protein Identity:
100
99.5
98.7
96.3
N.A.
91.8
91.4
N.A.
84.6
77.7
70.9
62.1
N.A.
46.1
48.4
41.4
29.3
Protein Similarity:
100
99.5
99.3
97.8
N.A.
95.9
95.7
N.A.
90.1
85.4
83.9
75.4
N.A.
64.1
65.6
60.8
37.6
P-Site Identity:
100
93.3
93.3
93.3
N.A.
53.3
53.3
N.A.
86.6
33.3
60
0
N.A.
0
0
13.3
20
P-Site Similarity:
100
93.3
93.3
93.3
N.A.
66.6
60
N.A.
93.3
40
73.3
13.3
N.A.
0
20
26.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
37.9
22.5
22.1
Protein Similarity:
N.A.
N.A.
N.A.
55.6
41.2
38
P-Site Identity:
N.A.
N.A.
N.A.
0
20
0
P-Site Similarity:
N.A.
N.A.
N.A.
20
26.6
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
6
6
0
0
48
6
6
6
0
0
0
0
0
% A
% Cys:
0
6
0
0
0
6
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
6
0
0
6
12
0
0
0
0
6
12
6
0
% D
% Glu:
6
0
6
6
0
6
0
6
0
6
0
6
6
36
42
% E
% Phe:
0
0
6
0
0
6
6
6
0
6
0
0
6
0
12
% F
% Gly:
0
0
0
6
6
6
0
6
48
0
53
6
0
12
18
% G
% His:
0
0
0
0
0
0
0
0
0
6
0
0
6
6
0
% H
% Ile:
6
12
0
0
0
6
0
0
0
0
0
0
6
0
0
% I
% Lys:
12
0
6
6
12
0
0
6
0
0
0
42
6
12
0
% K
% Leu:
0
6
42
6
12
53
6
0
6
0
12
0
0
0
0
% L
% Met:
0
0
6
0
0
0
0
0
0
0
0
0
0
0
6
% M
% Asn:
18
0
0
30
12
6
6
0
6
6
12
0
12
6
12
% N
% Pro:
0
48
6
6
59
6
0
0
6
0
0
6
6
6
6
% P
% Gln:
0
0
12
0
0
0
0
0
0
36
0
0
0
0
0
% Q
% Arg:
42
6
0
18
0
0
0
6
0
24
0
0
0
0
0
% R
% Ser:
0
12
0
12
0
0
12
53
12
6
12
12
42
18
6
% S
% Thr:
12
0
0
6
0
0
12
12
6
6
6
12
0
0
0
% T
% Val:
6
6
0
0
0
0
0
0
0
0
6
6
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
6
6
0
0
0
0
0
12
0
0
6
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _